TOUCH PERCEPTIONS ACROSS SKIN SITES: DIFFERENCES BETWEEN SENSITIVITY, DIRECTION DISCRIMINATION AND PLEASANTNESS

Touch perceptions across skin sites: differences between sensitivity, direction discrimination and pleasantness

Human skin is innervated with different tactile afferents over the body, which are found at varying densities.We investigate how the relationships between tactile pleasantness, sensitivity and discrimination differ across the skin.Tactile pleasantness was assessed by stroking a soft brush over the skin, using five velocities (0.3, 1, 3, 10, 30 cm s

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Non-additive modulation of synaptic transmission by serotonin, adenosine, and cholinergic modulators in the sensory thalamus

The thalamus relays sensory information to the cortex.Oscillatory activities of the thalamocortical network are modulated by monoamines, acetylcholine, and adenosine, and could be the key features characteristic of different vigilance states.Although the thalamus is almost always subjective to the actions of more than just one neuromodulator, repor

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